2019-nCoV Kutabogama Ikizamini cya Antibody (QDIC)
Ibisobanuro birambuye:
Innovita® 2019-nCoV IgM / IgG Ikizamini kigamije kumenya umubare munini wo kutabuza antibody kwanduza coronavirus (2019-nCoV) muri serumu yumuntu, plasma cyangwa amaraso yose (amaraso yintoki cyangwa amaraso yuzuye).
2019-nCoV ikubiyemo poroteyine enye zingenzi zubaka: S proteine, E proteyine, proteine M na proteine N.Agace ka RBD ka poroteyine irashobora guhuza na selile yumuntu yakira ACE2.Ubushakashatsi bwerekanye ko ingero zabantu bakize igitabo cyanduye coronavirus ari nziza muguhindura antibody.Kumenya antibody itabogamye irashobora gukoreshwa mugusuzuma ibimenyetso byanduye virusi no gusuzuma ingaruka nyuma yo gukingirwa.
Ihame:
Igikoresho ni quantum dot immunofluorescence chromatografiya kugirango tumenye 2019-nCoV RBD yihariye IgG itabuza antibodi muri serumu yumuntu, plasma cyangwa amaraso yose (amaraso yintoki n'amaraso yose).Nyuma yikigereranyo gishyizwe kumurongo neza, niba intumbero yo kutabuza antibodiyite irenze igipimo cyo hasi cyane, antibodiyite ya RBD yihariye igabanya igice cyangwa antigen yose ya RBD yanditseho microsperes ya kwantum kugirango ikore ubudahangarwa bw'umubiri.Noneho ubudahangarwa bw'umubiri buzimuka hafi ya nitrocellulose.Iyo bageze mukarere ka test (T umurongo), uruganda ruzitwara nimbeba irwanya abantu IgG (γ urunigi) itwikiriye kuri nitrocellulose hanyuma ikore umurongo wa fluorescent.Soma ibimenyetso bya fluorescence hamwe na fluorescence immunoassay isesengura.Agaciro kerekana ibimenyetso bifitanye isano nibirimo byo kutabogama antibodiyumu.
Niba urugero rurimo RBD yihariye itabuza antibodiyite cyangwa ntayo, umurongo wo kugenzura ugomba guhora ugaragara mumadirishya y'ibisubizo niba inzira yikizamini ikozwe neza kandi reagent ikora nkuko byateganijwe.Iyo antibody yinkoko IgY yanditseho quantum dot microsperes yimukiye kumurongo ugenzura (C umurongo), izafatwa nihene irwanya inkoko antibody antibody yandikiwe kumurongo wa C, hanyuma havuka umurongo wa fluorescent.Igenzura ry'umurongo (C umurongo) rikoreshwa nkigenzura ryimikorere.
Ibigize:
Ibigize | Umubare | Ibisobanuro |
IFU | 1 | / |
Cassette | 20 | Buri mufuka wafunze urimo igikoresho kimwe cyo gupima hamwe na desiccant |
Kugereranya | 3mL * 1 vial | 20mM PBS, Sodium Casein, ProClin 300 |
Micropipette | 20 | Micropipette ifite umurongo wa 20μL |
Lancet | 20 | / |
Inzoga | 20 | / |
Uburyo bwo Kwipimisha:
Collection Ikusanyirizo ry'amaraso
● Soma ibisubizo hamwe nisesengura rya fluorescence